Androgen Insensitivity Syndrome

Androgen insensitivity syndrome is a condition of genetic origin in which the body does not respond in the usual way to male hormones (androgens), which affects the development of sexual characteristics despite a male chromosomal makeup.

How it presents: Depending on the degree of insensitivity, one may notice a physical appearance that does not match what would be expected from the chromosomes, an absence or scarcity of body hair and, at times, a lack of menstruation during adolescence.

Why it arises: It is related to variants in the androgen receptor gene, so it usually has a hereditary component.

Which specialist treats it? The evaluation falls to endocrinology, which studies hormonal balance, and it is often accompanied by support from psychology for the emotional support of the person and their family. If this is suspected, the most prudent course is to seek a professional evaluation that guides each case individually.